US equities experienced their sharpest decline since July on Wednesday, driven by hotter-than-expected inflation data that disproportionately impacted technology and AI infrastructure sectors. The S&P 500 fell 1.1%, marking its largest one-day drop since July 29, while the Nasdaq Composite declined 1.9%, its biggest single-day loss since July 23. In contrast, the Dow Jones Industrial Average slipped only 0.1%. Major tech decliners included CoreWeave, which dropped 16%, Nebius down 11%, and Oracle falling 9%. Within the broader AI infrastructure space, 21 of the 23 stocks tracked by PRISM’s AI Data Center and Infrastructure Index declined, averaging a 7.46% loss.

Bitcoin miners, many of whom have diversified into AI infrastructure, faced significant selling pressure. TeraWulf shares fell 12.64%, while Core Scientific, Cipher Mining, and IREN declined by 12.44%, 12.35%, and 12.2%, respectively. Other affected companies included Riot Platforms, Bitdeer Technologies, MARA, and CleanSpark. The selloff was triggered by US consumer prices rising 3.7% in September year-over-year, exceeding economists' expectations of 3.6% and remaining well above the Federal Reserve's 2% target. Higher gasoline prices linked to Middle East conflicts were cited as a primary driver of the inflation spike.

The inflation report heightened market expectations for an October Federal Reserve interest-rate hike, with implied probabilities briefly surpassing 50% before retreating. However, San Francisco Fed President Mary Daly stated there was no urgency to act immediately, noting that further hikes might be needed but emphasizing the availability of time to assess limited information.