Phemex CEO Federico Variola described artificial intelligence as a "net negative" for the cryptocurrency sector during an interview on Cointelegraph’s Chain Reaction. Despite Phemex announcing an AI-focused transformation in February, Variola argued that the technology has diverted liquidity away from crypto while empowering malicious actors to exploit protocols more effectively.

Variola highlighted specific incidents, including a July attack that drained roughly $116 million in Bitcoin from over 5,200 addresses due to a Coldcard hardware wallet flaw believed to be discovered via AI. He warned that these threats increase cybersecurity costs for smaller teams and could push the industry toward centralization by making self-custody and decentralized finance less appealing to retail users.